Doxapram hydrochloride monohydrate( AHR 619 )

Catalog No. M15718 CAS No. 7081-53-0

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Doxapram hydrochloride monohydrate
Note

Research use only, not for human use.
Brief Description

Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
Description

Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
In Vitro

——
In Vivo

——
Synonyms

AHR 619
Pathway

Cell Cycle/DNA Damage
Target

Potassium Channel
Recptor

TASK-1| TASK-1/TASK-3 heterodimeric| TASK-3
Research Area

Neurological Disease
Indication

——

CAS Number

7081-53-0
Formula Weight

432.99
Molecular Formula

C24H33ClN2O3
Purity

>98% (HPLC)
Solubility

Ethanol: 2 mg/mL (4.61 mM); Water: 25 mg/mL (57.73 mM); DMSO: 87 mg/mL (200.93 mM)
SMILES

O=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl.[H]O[H]
Chemical Name

2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-, monohydrochloride, monohydrate

1. Yost CS. CNS Drug Rev. 2006 Fall-Winter;12(3-4):236-49.

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