Doxapram hydrochloride monohydrate
CAS No. 7081-53-0
Doxapram hydrochloride monohydrate ( AHR 619 )
Catalog No. M15718 CAS No. 7081-53-0
Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
25MG | 46 | In Stock |
|
50MG | 61 | In Stock |
|
100MG | 105 | In Stock |
|
200MG | 164 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDoxapram hydrochloride monohydrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionDoxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
-
DescriptionDoxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
-
SynonymsAHR 619
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorTASK-1; TASK-1/TASK-3 heterodimeric; TASK-3
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number7081-53-0
-
Formula Weight432.99
-
Molecular FormulaC24H33ClN2O3
-
Purity>98%(HPLC)
-
SolubilityEthanol: 2 mg/mL (4.61 mM); Water: 25 mg/mL (57.73 mM); DMSO: 87 mg/mL (200.93 mM)
-
SMILESO=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl.[H]O[H]
-
Chemical Name2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-, monohydrochloride, monohydrate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yost CS. CNS Drug Rev. 2006 Fall-Winter;12(3-4):236-49.
molnova catalog
related products
-
VU591 hydrochloride
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM).?Thought to block the intracellular pore of the Kir1.1 channel.?Exhibits no effect on Kir7.1 at concentrations up to 10 μM;?does not inhibit Kir2.1, Kir2.3 or Kir4.1.?
-
Almitrine dimesylate
Almitrine dimesylate inhibits selectively the Ca2+-dependent K+ channel and that in rat chemoreceptor cellsused in the treatment of hypoxemic chronic lung diseases.
-
KCNQ1 activator-1?
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- is a potent KCNQ1 channel activator that can be used in long QT syndrome (LQTS) studies.